Blood tests and an MRI finally confirmed the doctor’s suspicion: Yawn had a tumor in her pituitary gland — a pea-size organ at the base of the brain — that was causing the gland to release too much adrenocorticotropic hormone. That, in turn, flooded her body with cortisol, a steroid hormone that’s normally released in response to stress or danger. The resulting condition is called Cushing disease.

Read more at https://cushings.invisionzone.com/topic/56889-media-attention-cushings-on-today/

We present a 9-year-old boy who presented at age 4 with cyclical Cushing syndrome and was eventually diagnosed with a novel, previously unreported, unpublished variant in PRKAR1A associated with Carney complex. He was treated with unilateral left adrenalectomy. At 1-year follow-up, he continues to be in remission of his symptoms of Cushing syndrome.

https://cushings.invisionzone.com/topic/57870-unilateral-adrenalectomy-for-pediatric-cyclical-cushing-syndrome-with-novel-prkar1a-variant-associated-carney-complex/

The most common cause of Cushing syndrome (CS) is exposure to exogenous glucocorticoids. There is an increasing incidence of adulterated over-the-counter (OTC) supplements containing steroids.

Read more at https://cushings.invisionzone.com/topic/57624-exogenous-cushing-syndrome-and-hip-fracture-due-to-over-the-counter-supplement-artri-king/

The trial will assess the drug's efficacy, tolerability, and safety in individuals with Cushing's.

https://cushings.invisionzone.com/topic/57785-sterotherapeutics-begins-phase-ii-trial-for-st-002-targeting-cushing%E2%80%99s-syndrome/

The higher IGF-1 index was independently associated with lower prevalence of low bone mass in young CD patients, and IGF-1 might play an important role in the pathogenesis of CD-caused low bone mass.

Read more at https://cushings.invisionzone.com/topic/57619-association-of-igf-1-level-with-low-bone-mass-in-young-patients-with-cushing%E2%80%99s-disease/

Cushing’s disease is a progressive pituitary disorder in which there is an excess of cortisol in the body. While the disease can be treated surgically, this option is not possible for all patients. This is one of the approved medications that assist in controlling cortisol levels in people with Cushing’s disease.

Recorlev was approved by the FDA in December 2021 to treat those Cushing’s patients for whom surgery is not a choice or has failed to lower cortisol levels.

Read more at https://cushings.invisionzone.com/topic/56549-meds-recorlev/

Graphic Era Hospital has achieved a remarkable mileston by successfully treating two complex cases of the rare hormonal disorder Cushing’s Disease in Dehradun. The hospital’s experts used advanced technology and surgical skills to give the patients a new lease on life, marking this significant achievement.

https://cushings.invisionzone.com/topic/57868-graphic-era-hospital%E2%80%99s-milestone-treatment-of-two-complex-cases/

HSD-1 inhibition with clofutriben is a completely novel approach to the treatment of endogenous Cushing’s syndrome that may overcome many of the serious problems with current therapies, including major safety, tolerability, and complexity issues such as the risk of adrenal insufficiency and adrenal crisis.

Read more at https://cushings.invisionzone.com/topic/57761-sparrow-pharmaceuticals-announces-completion-of-phase-2-trial-and-fda-orphan-drug-designation-of-clofutriben-for-endogenous-cushing%E2%80%99s-syndrome/

Posterior pituitary tumors (PPTs) are extremely rare, with fewer than 400 cases reported to date. In 2022, the WHO classified four types of tumors originating from the posterior pituitary

Read more at https://cushings.invisionzone.com/topic/57780-oncocytic-pituicytoma-in-a-patient-with-cushings-disease/

I certainly know this to be true   I'm an 18 year survivor of yet another disease that I shouldn't have gotten:  kidney cancer.

https://cushings.invisionzone.com/topic/57758-cancer-risk-elevated-for-adults-after-cushing%E2%80%99s-syndrome-diagnosis/

She got Cushing’s Syndrome from abundant steroid injections due to a severe back injury and it has rendered her “comatose”.   She has no energy, she sleeps all the time, and I miss her and am lonely when she is in this state, which is all the time.

https://cushingsbios.com/2025/11/28/trish-steroid-induced-bio/

We present a 9-year-old boy who presented at age 4 with cyclical Cushing syndrome and was eventually diagnosed with a novel, previously unreported, unpublished variant in PRKAR1A associated with Carney complex. He was treated with unilateral left adrenalectomy. At 1-year follow-up, he continues to be in remission of his symptoms of Cushing syndrome.

https://cushings.invisionzone.com/topic/57870-unilateral-adrenalectomy-for-pediatric-cyclical-cushing-syndrome-with-novel-prkar1a-variant-associated-carney-complex/

Crinetics Pharmaceuticals is conducting a study titled ‘A Phase 1b/2a Open-label Multiple-ascending Dose Exploratory Study of CRN04894 in ACTH-dependent Cushing’s Syndrome.’ This study aims to evaluate the safety, tolerability, and pharmacokinetics of CRN04894, an ACTH receptor antagonist, in treating Cushing’s Syndrome, a condition characterized by excessive cortisol production. The study’s significance lies in its potential to offer a new treatment avenue for patients with Cushing’s disease or Ectopic ACTH Syndrome.

https://cushings.invisionzone.com/topic/57905-crinetics-pharma%E2%80%99s-promising-study-on-crn04894-for-cushing%E2%80%99s-syndrome-a-potential-game-changer/

Laparoscopic adrenalectomy is the standard treatment for adrenal tumors caused by Cushing's syndrome. However, few pregnant women have undergone adrenalectomy because of the risk of general anesthesia and surgery.

Read more at https://cushings.invisionzone.com/topic/57639-cushings-syndrome-in-pregnancy-in-which-laparoscopic-adrenalectomy-was-safely-performed-by-a-retroperitoneal-approach/

While many patients with Cushing syndrome have a delayed diagnosis, this case highlights the critical need to increase awareness of the signs and symptoms of hypercortisolism and to improve the understanding of appropriate screening tests among nonendocrine providers.

Read more at https://cushings.invisionzone.com/topic/57707-delayed-diagnosis-of-ectopic-cushing-syndrome/

The most common cause of Cushing syndrome (CS) is exposure to exogenous glucocorticoids. There is an increasing incidence of adulterated over-the-counter (OTC) supplements containing steroids.

Read more at https://cushings.invisionzone.com/topic/57624-exogenous-cushing-syndrome-and-hip-fracture-due-to-over-the-counter-supplement-artri-king/

The higher IGF-1 index was independently associated with lower prevalence of low bone mass in young CD patients, and IGF-1 might play an important role in the pathogenesis of CD-caused low bone mass.

Read more at https://cushings.invisionzone.com/topic/57619-association-of-igf-1-level-with-low-bone-mass-in-young-patients-with-cushing%E2%80%99s-disease/

Cushing disease (CD) is the most common form of adrenocorticotropin (ACTH)-dependent Cushing syndrome (CS), whereas unilateral adrenal adenoma is the most common cause of ACTH-independent CS. However, the occurrence of different subtypes of CS in a single individual is very rare.

https://cushings.invisionzone.com/topic/57836-a-second-look-at-cushing-disease-hypercortisolism-recurrence-from-another-gland/

Like most everything else in my life, having had Cushing's (pituitary) made this surgery more difficult.  My surgeon had to plan with my endocrinologist how much cortisol I'd need during the operation, then I had to stay overnight to get me successfully weaned off the cortisone again.

Read more at https://cushings.invisionzone.com/topic/57682-what-was-the-most-memorable-thing-that-happened-to-you-last-year/

In the media: Jessica and Justin, siblings who both had pituitary tumors.

https://cushingsbios.com/2025/12/29/jessica-and-justin-siblings-in-the-media/

By Dr. Lewis Blevins: This book is perhaps something a little different than most would expect. Firstly, it's a single-author book on Cushing's syndrome. It is not, like most textbooks, a compendium of edited submissions from multiple authors where there are often divergent opinions from one chapter to the next. Instead, it's a treatise reflecting my education and experience. It is not referenced but instead each chapter is followed by suggested readings. It represents my thoughts, understanding and a personal reflection on a career of evaluating a multitude of patients suspected of having the disorder and treating those confirmed to have hypercortisolism due to one cause or another. It reflects my perspectives of the art and science of the field.

More info at https://cushings.invisionzone.com/topic/57752-cushings-a-comprehensive-guide-to-understanding-a-devastating-condition/

Seliciclib (R-roscovitine) has been shown in preclinical studies to inhibit neoplastic corticotroph proliferation and the production of adrenocorticotropic hormone (ACTH) in the pituitary gland. Therefore, for a study, researchers sought to investigate the effectiveness of seliciclib as a pituitary-targeting treatment for patients with Cushing’s disease (CD).

Read more at https://cushings.invisionzone.com/topic/57604-seliciclib-for-the-treatment-of-cushing%E2%80%99s-disease-targeting-pituitary/

Graphic Era Hospital has achieved a remarkable mileston by successfully treating two complex cases of the rare hormonal disorder Cushing’s Disease in Dehradun. The hospital’s experts used advanced technology and surgical skills to give the patients a new lease on life, marking this significant achievement.

https://cushings.invisionzone.com/topic/57868-graphic-era-hospital%E2%80%99s-milestone-treatment-of-two-complex-cases/

A 48-year-old male with a history of hypertension presented to his primary care physician with complaints of bilateral leg swelling, occasional shortness of breath, dizziness, and a general feeling of malaise persisting for 10 days. The patient reported increased water intake and urinary frequency without dysuria. The patient was diagnosed with hypertension eight months ago. He experienced progressive muscle weakness over two months, hindering his ability to perform daily activities, including using the bathroom. 

Read more at https://cushings.invisionzone.com/topic/57740-unveiling-the-uncommon-cushing%E2%80%99s-syndrome-cs-masquerading-as-severe-hypokalemia/

Posterior pituitary tumors (PPTs) are extremely rare, with fewer than 400 cases reported to date. In 2022, the WHO classified four types of tumors originating from the posterior pituitary

Read more at https://cushings.invisionzone.com/topic/57780-oncocytic-pituicytoma-in-a-patient-with-cushings-disease/

Cushing’s disease (CD) is associated with phenotypic traits and comorbidities that may persist after the normalization of cortisol levels. Medical therapy is usually given in recurrent or persistent CD after transsphenoidal surgery. We aimed to investigate the impact of long-term normalization of daily cortisol secretion on clinical picture and cardiometabolic comorbidities, comparing surgical remission to medical treatment.

https://cushings.invisionzone.com/topic/57817-cardiometabolic-complications-after-cushing%E2%80%99s-disease-remission/

We report the case of a patient with double functional pituitary adenomas causing acromegaly and subclinical Cushing's disease. A 45-year-old woman was referred to our Department for suspected acromegaly. Her past medical history included diabetes mellitus treated with oral antidiabetic drugs and hypertension.

https://cushings.invisionzone.com/topic/57847-double-synchronous-functional-pituitary-adenomas-causing-acromegaly-and-subclinical-cushing-disease/

Our study demonstrate a significant improvement in serum lipid levels after treatment of Cushings Syndrome. Since the cardiovascular complications of hypercortisolism depend on several factors, further studies are needed to determine whether this directly translates into an adequate reduction in the risk of major cardiovascular events.

https://cushings.invisionzone.com/topic/57931-the-effect-of-hypercortisolism-treatment-on-dyslipidemia-in-cushing-syndrome/

Cushing's has appeared several times in the media.  Jayne Kerns encouraged Zastrow to check out a Cushing's Web site, which Zastrow did. Every symptom listed matched her condition. Her doctor ran some tests, and the results confirmed Zastrow had Cushing's, a hormonal disorder often brought  on by a tumor.

https://cushingsbios.com/2025/11/29/laura-in-the-media/

Please add your bio. Your information will help others.

I would like to add that if anyone would like to do something for the Cushing's Awareness Challenge but you don't have (or want to have) a blog, why not consider adding your bio to the website this month?

More info at https://cushingsbios.com/2024/10/28/we-have-a-new-bio-form/

Add your location and diagnosis to our Cushing's World Map.
Helpful Doctor locations are being added to this map, as well

See the Map at https://drive.google.com/open?id=1NLdGqTJyaJOvxegUnUR_slLRcYyMsVbJ&usp=sharing

We present a 9-year-old boy who presented at age 4 with cyclical Cushing syndrome and was eventually diagnosed with a novel, previously unreported, unpublished variant in PRKAR1A associated with Carney complex. He was treated with unilateral left adrenalectomy. At 1-year follow-up, he continues to be in remission of his symptoms of Cushing syndrome.

https://cushings.invisionzone.com/topic/57870-unilateral-adrenalectomy-for-pediatric-cyclical-cushing-syndrome-with-novel-prkar1a-variant-associated-carney-complex/

The most common cause of Cushing syndrome (CS) is exposure to exogenous glucocorticoids. There is an increasing incidence of adulterated over-the-counter (OTC) supplements containing steroids.

Read more at https://cushings.invisionzone.com/topic/57624-exogenous-cushing-syndrome-and-hip-fracture-due-to-over-the-counter-supplement-artri-king/

Since I just had Mohs surgery for squamous cell carcinoma, I immediately went to amazon to search for nicotinamide.

Read more at https://maryomedical.com/2021/05/30/testing-vitamin-b3/

The higher IGF-1 index was independently associated with lower prevalence of low bone mass in young CD patients, and IGF-1 might play an important role in the pathogenesis of CD-caused low bone mass.

Read more at https://cushings.invisionzone.com/topic/57619-association-of-igf-1-level-with-low-bone-mass-in-young-patients-with-cushing%E2%80%99s-disease/

I have been on the health journey for a number of years. It was a friend who gave me the name of Cushing’s and had I been tested. Tested?! Never heard of it.

Went online and saw the symptoms. Felt that the missing piece of the puzzle was found.

https://cushingsbios.com/2025/12/30/sandy-kindredspirit-pituitary-bio/

There are several home cortisol tests available to purchase over the counter or online. These allow a person to take a sample of blood, urine, or saliva before sending it off for analysis.

After taking a home cortisol test, people can usually receive their results within 2–5 days online or via a telephone call with a healthcare professional.

However, there are currently no studies investigating the reliability of these home cortisol tests. Therefore, people should follow up on their test results with a healthcare professional.

Read more at https://cushings.invisionzone.com/topic/55639-home-cortisol-tests-3-of-the-best/

Some pain is normal after any surgery. Different people have different levels of sensitivity to pain. In general, you should experience a little less pain every day. Pain is usually worse in the evening when you are trying to go to sleep. Do not be afraid to take the pain medicine prescribed for you, particularly before you go to sleep, but you can stop taking it if you are comfortable. Most pain medications cause constipation and they can also cause drowsiness. Do not drive or operate power tools after you take narcotic pain medications. If you have only mild discomfort, try taking extra-strength Tylenol® as directed.

https://cushings-help.com/2024/10/30/adrenalectomy-and-bla/

The diagnosis of Cushing's Syndrome is often difficult due to the insidious onset of hypercortisolism, in absence of relevant early signs of the disease, as well as the rarity of the disease in childhood. For these reasons, the time to diagnosis has been reported as a mean of 33 months (95% CI 29–38) and not dissimilar to adult population.

https://cushings.invisionzone.com/topic/57762-cushing-syndrome-in-paediatric-population/

Paraneoplastic Cushing syndrome (PCS) is a rare manifestation of ectopic adrenocorticotropic hormone (ACTH) production, mostly associated with bronchial carcinoid and small cell lung cancer (SCLC).

https://cushings.invisionzone.com/topic/57932-a-second-look-at-refractory-edema-delayed-diagnosis-of-paraneoplastic-cushing%E2%80%99s-syndrome-in-small-cell-lung-cancer/

Cushing's Disease can be treated, but only with the right doctor and diagnosis. 

We explore the barriers that make some patients endure years of symptoms before finding relief.

https://cushings.invisionzone.com/topic/57933-morning-medical-update-cushings-disease/

Scientists now tell us there is something in our waters that we least expected.

That “something” is a class of chemicals called endocrine disruptors, and Dr. Vicki Blazer, a fisheries biologist at the United States Geological Survey, thinks the chemicals are responsible for the high concentrations of intersex fish found in the Potomac, and other rivers in the mid-Atlantic.

https://cushieblog.com/2025/12/30/environmental-issues-and-cushings/

Graphic Era Hospital has achieved a remarkable mileston by successfully treating two complex cases of the rare hormonal disorder Cushing’s Disease in Dehradun. The hospital’s experts used advanced technology and surgical skills to give the patients a new lease on life, marking this significant achievement.

https://cushings.invisionzone.com/topic/57868-graphic-era-hospital%E2%80%99s-milestone-treatment-of-two-complex-cases/

Three young female patients with a history of generalized body pain were diagnosed with fibromyalgia. They visited several specialities which related patients' symptoms to their previous diagnosis of fibromyalgia and were treated symptomatically. These patients developed a multitude of clinical features including fractures, hypertension, abnormal weight gain, proximal myopathic pain and bruising. They were seen by rheumatologists whose assessment was that their clinical features were not entirely due to fibromyalgia and suspected that patients have a possible underlying endocrine cause. Patients were referred to an endocrinologist for further tests with suspicion of Cushing’s syndrome. Laboratory tests and imaging confirmed a diagnosis of Cushing’s syndrome. Two of them had adrenal adenoma and one had iatrogenic corticosteroid use. These cases emphasize the need for thorough clinical evaluation for patients who are thought to have fibromyalgia. Fibromyalgia is a diagnosis of exclusion.

Read more at https://cushings.invisionzone.com/topic/57756-cushing%E2%80%99s-syndrome-masquerading-as-fibromyalgia-a-case-series/

Posterior pituitary tumors (PPTs) are extremely rare, with fewer than 400 cases reported to date. In 2022, the WHO classified four types of tumors originating from the posterior pituitary

Read more at https://cushings.invisionzone.com/topic/57780-oncocytic-pituicytoma-in-a-patient-with-cushings-disease/

A 29-year-old Japanese pregnant woman, G5P3A1, conceived spontaneously and was referred to our hospital because of uncontrolled hypertension at 24 weeks of gestation. On admission, she presented with physical findings characteristic of Cushing's syndrome (CS), such as moon face, buffalo hump, and reddish-purple striae. Laboratory examination revealed hyperglycemia and hypercortisolism with suppressed adrenocorticotropic hormone levels. Imaging studies revealed a right adrenocortical adenoma, and the patient was clinically diagnosed with adrenal CS. 

https://cushings.invisionzone.com/topic/57924-adrenal-cushing%E2%80%99s-syndrome-in-pregnancy-complicated-by-fetal-growth-restriction-following-retroperitoneoscopic-adrenalectomy/

Herein, national data of the clinical experience on paediatric CD have been presented. Our findings highlight that presenting complaints may be subtle in children, the sensitivities of the diagnostic tests are very variable and require a careful interpretation, and MRI fails to detect adenoma in approximately one-third of cases. Finally, clinicians should be aware of the recurrence of the disease during the follow-up after surgery.

Read more at https://cushings.invisionzone.com/topic/57658-clinical-features-diagnosis-and-treatment-outcomes-of-cushings-disease-in-children-a-multicenter-study/

We report a case of a 16-year-old female with recurrent Cushing’s disease secondary to a pituitary microadenoma, confirmed by elevated urinary free cortisol and magnetic resonance imaging (MRI). It was initially treated with transsphenoidal resection in 2019; disease recurrence was confirmed and again treated in 2024.

https://cushings.invisionzone.com/topic/57848-reconstructive-liposuction-for-residual-lipodystrophy-after-remission-of-cushing%E2%80%99s-disease/

I’ve been gaining weight for about 3 1/2 yrs since having my thyroid removed due to a 25 yr old nodule that was calcified. My thyroid levels have always been good, before and after removal. There were A typical cells in the nodule, that’s why they advised removing the thyroid.

As I gain weight and have lumps of inflammation now over all of my body, all I have been told is to eat less and exercise more. Even though I have told my drs that I barely eat at all.

https://cushingsbios.com/2025/11/30/laura-f-undiagnosed-bio/

I was drawn to this blog post because the author mentioned that she had both Cushing’s and cancer, a kind of unusual combination.

1974 to Today: Seal it up
By Experience
I still haven’t heard what the consensus is on my aftercare: Cushing’s and Cancer. I don’t know what I will be expecting to feel like after surgery. My endocrinologist said that I should get sick after the surgery and need some kind of …
1974 to Today – http://1974totoday.blogspot.com/

We present a 9-year-old boy who presented at age 4 with cyclical Cushing syndrome and was eventually diagnosed with a novel, previously unreported, unpublished variant in PRKAR1A associated with Carney complex. He was treated with unilateral left adrenalectomy. At 1-year follow-up, he continues to be in remission of his symptoms of Cushing syndrome.

https://cushings.invisionzone.com/topic/57870-unilateral-adrenalectomy-for-pediatric-cyclical-cushing-syndrome-with-novel-prkar1a-variant-associated-carney-complex/

Cushing's Syndrome, a rare but complex endocrine disorder characterized by excessive cortisol production, presents unique challenges and risks during pregnancy. Recent advancements in medical understanding have led to greater awareness of the implications of this syndrome when coupled with conditions like diabetes insipidus, particularly in pregnant patients. The coexistence of these disorders emphasizes the need for a multidisciplinary approach to manage these high-risk pregnancies effectively.

https://cushings.invisionzone.com/topic/57872-pregnancy-case-cushing%E2%80%99s-syndrome-with-diabetes-insipidus/

The most common cause of Cushing syndrome (CS) is exposure to exogenous glucocorticoids. There is an increasing incidence of adulterated over-the-counter (OTC) supplements containing steroids.

Read more at https://cushings.invisionzone.com/topic/57624-exogenous-cushing-syndrome-and-hip-fracture-due-to-over-the-counter-supplement-artri-king/

The higher IGF-1 index was independently associated with lower prevalence of low bone mass in young CD patients, and IGF-1 might play an important role in the pathogenesis of CD-caused low bone mass.

Read more at https://cushings.invisionzone.com/topic/57619-association-of-igf-1-level-with-low-bone-mass-in-young-patients-with-cushing%E2%80%99s-disease/

In 2011, I realized I had Cushing’s Syndrome. I was a 30 year old male with several complications: swollen feet, swollen legs, stomach looked 9 months pregnant, hair fell out, memory loss, couldn’t sleep, couldn’t eat, diabetes, mood swings, depression, urination every hour during the night, bright pink stretch marks, etc.

After changing my doctors several times for misdiagnosis, I was finally tested for Cushing’s Disease/Syndrome. I contacted the National Institute of Health and doctors advised me to come in immediately. I survived 2 months living at NIH, while doctors ran several tests to determine if I had Cushing’s Disease or Cushing’s Syndrome. I had Cushing’s Syndrome and my tumor was found in my right adrenal gland.

https://cushingsbios.com/2025/12/31/brian-brian-adrenal-bio/

I have a giant buffalo hump on the back of the neck with vertical blue/purple lines below it.

I also have lipomas not symetrical across my upper back.  Then there are two symetrical lumps near each arm pit.

Two lab results come back saying I have a normal cortisol level.

https://cushingsbios.com/2025/12/31/h-lane-sunshine-undiagnosed-bio/

I have a pituitary microadenoma and am still doing all kinds of testing to see if it is active.  I’ve gotten two clinically high indicative Cushing’s test results so far–midnight serum cortisol of 14 and 24 hour uring 17OHS of 11.5.

We are still testing.

https://cushingsbios.com/2025/12/31/donna-dutchie-pituitary-bio/

No formal diagnosis yet.  Self-diagnosis by overhwhelming clinical suspicion, including CT scan evidence of growing left adrenal adenoma.

Clueless endrocrinologist who has missed the diagnosis for the whole two years I have been consulting her, including missing an acute state caused by prescribed Prednisone that resulted in my being pushed into her office in a wheelchair.  She didn’t even comment on that. :-O

https://cushingsbios.com/2025/12/31/rosemary-berry-undiagnosed-bio/

Graphic Era Hospital has achieved a remarkable mileston by successfully treating two complex cases of the rare hormonal disorder Cushing’s Disease in Dehradun. The hospital’s experts used advanced technology and surgical skills to give the patients a new lease on life, marking this significant achievement.

https://cushings.invisionzone.com/topic/57868-graphic-era-hospital%E2%80%99s-milestone-treatment-of-two-complex-cases/

Cyclic Cushing syndrome (CCS) is a rare variant of Cushing syndrome (CS) characterized by intermittent episodes of cortisol peaks alternating with variable periods of normal or subnormal adrenocorticotropic hormone (ACTH) and cortisol levels.

https://cushings.invisionzone.com/topic/57906-three-cases-of-ectopic-cyclic-cushing-syndrome-a-new-square-wave-variant/

Facial plethora is a main symptom of Cushing syndrome, a rare condition that’s caused by high levels of cortisol, known as the stress hormone.

Read more at https://cushings.invisionzone.com/topic/56564-what-is-facial-plethora/#comment-477092

Posterior pituitary tumors (PPTs) are extremely rare, with fewer than 400 cases reported to date. In 2022, the WHO classified four types of tumors originating from the posterior pituitary

Read more at https://cushings.invisionzone.com/topic/57780-oncocytic-pituicytoma-in-a-patient-with-cushings-disease/

We present a case of anorexia nervosa (AN), which is a rare cause of hypercortisolism. We discuss the case of a female patient with a body mass index (BMI) of 12.4 kg/m2 who was referred to us because of hypercortisolism. When the patient was evaluated for Cushing's syndrome (CS), the clinical presentation was not suggestive.

https://cushings.invisionzone.com/topic/57873-a-rare-case-of-hypercortisolemia-alongside-anorexia-nervosa/

In our Daily Dose, a viewer is asking about hormone problems that can cause your face to become round. Dr. Lacy Anderson joined News 9 to explain how some hormone disorders, like Cushing syndrome work.

Read more at https://cushings.invisionzone.com/topic/57733-cushing-syndrome-and-hormone-disorders/

The first-line treatment for Cushing’s disease is transsphenoidal surgery for pituitary tumor resection. Ketoconazole has been used as a second-line drug despite limited data on its safety and efficacy for this purpose.

Read more at https://cushings.invisionzone.com/topic/57605-ketoconazole-as-second-line-treatment-for-cushing%E2%80%99s-disease-after-transsphenoidal-surgery/

Relacorilant was deemed well tolerated in the trial. The most common adverse events were nausea, edema, back and extremity pain and fatigue, all of which were mild or moderate in nature and are consistent with symptoms people experience after surgery or the start of therapy to treat hypercortisolism.

Read more at https://cushings.invisionzone.com/topic/57728-investigational-cushing%E2%80%99s-syndrome-medication-reduces-bp-glucose-in-open-label-trial/

Abstract

This case report describes a 42-year-old female with a rare pheochromocytoma presenting without classic Cushingoid features but with uncontrolled hypertension, type 2 diabetes, and recurrent headaches. Despite the absence of typical signs, biochemical analysis revealed elevated cortisol and ACTH levels, and imaging showed a 6 cm adrenal mass. The patient was stabilized preoperatively with alpha-blockers and metyrapone before undergoing a successful laparoscopic adrenalectomy. Histopathology confirmed pheochromocytoma with aggressive features. Postoperatively, her blood pressure and symptoms improved, and her cortisol levels normalized. This case underscores the diagnostic challenges of ACTH-secreting pheochromocytomas without classic hypercortisolism signs and emphasizes the need for thorough endocrine and imaging assessments. Surgical resection remains the definitive treatment, with long-term follow-up essential to monitor for recurrence. This case contributes to the limited literature on the coexistence of pheochromocytoma and ectopic ACTH secretion.

https://cushings.invisionzone.com/topic/57818-ectopic-acth-secreting-pheochromocytoma-without-typical-signs-of-cushing-syndrome/

We present a 9-year-old boy who presented at age 4 with cyclical Cushing syndrome and was eventually diagnosed with a novel, previously unreported, unpublished variant in PRKAR1A associated with Carney complex. He was treated with unilateral left adrenalectomy. At 1-year follow-up, he continues to be in remission of his symptoms of Cushing syndrome.

https://cushings.invisionzone.com/topic/57870-unilateral-adrenalectomy-for-pediatric-cyclical-cushing-syndrome-with-novel-prkar1a-variant-associated-carney-complex/

Cushing syndrome (CS) and Mild Autonomous Cortisol Secretion syndrome (MACS) are states of endogenous hypercortisolemia, associated with multiple metabolic complications.

https://cushings.invisionzone.com/topic/57887-liver-impairment-and-medical-management-of-cushing-syndrome-and-macs-provisionally/

We describe a case of a 56-year-old woman with a history of recurrent pituitary adenoma, not well followed, and known comorbidities of coronary artery disease, hypertension, and type 2 diabetes mellitus. She arrived with severely high blood pressure and signs pointing to hypercortisolism. Further evaluation revealed left ventricular hypertrophy, reduced global longitudinal strain, and preserved left ventricular ejection fraction, consistent with heart failure with preserved ejection fraction (HFpEF). Workup for amyloidosis was negative.

This case highlights that chronic hypercortisolism may cause pathophysiological changes in the heart, leading to HFpEF, and may induce myocardial fibrosis and impaired myocardial mechanics, producing an echocardiographic pattern that can mimic infiltrative cardiomyopathy. Recognition of this overlap is crucial to avoid misdiagnosis and to ensure timely endocrine and cardiovascular management.

https://cushings.invisionzone.com/topic/57888-global-longitudinal-strain-reduction-with-apical-sparing-in-cushing-syndrome-related-heart-failure-with-preserved-ejection-fraction-hfpef/

“In general, cortisol levels tend to peak in the late morning and gradually decline throughout the day,” he explains. “When a stressful event occurs, the increased cortisol will work alongside our ‘fight or flight’ mechanisms to either upregulate or downregulate bodily functions. [Affected systems include] the central nervous system, cardiovascular system, gastrointestinal system, or immune system.”

Read more at https://cushings.invisionzone.com/topic/57552-basics-what-causes-abnormal-cortisol-levels/

The most common cause of Cushing syndrome (CS) is exposure to exogenous glucocorticoids. There is an increasing incidence of adulterated over-the-counter (OTC) supplements containing steroids.

Read more at https://cushings.invisionzone.com/topic/57624-exogenous-cushing-syndrome-and-hip-fracture-due-to-over-the-counter-supplement-artri-king/

Patients with Cushing syndrome and mild autonomous cortisol secretion experienced similar degrees of sleep impairment.

https://cushings.invisionzone.com/topic/57907-sleep-impairment-similar-in-cushing-syndrome-mild-autonomous-cortisol-secretion/

The higher IGF-1 index was independently associated with lower prevalence of low bone mass in young CD patients, and IGF-1 might play an important role in the pathogenesis of CD-caused low bone mass.

Read more at https://cushings.invisionzone.com/topic/57619-association-of-igf-1-level-with-low-bone-mass-in-young-patients-with-cushing%E2%80%99s-disease/

As a rare endocrine disorder, Cushing’s Syndrome (Cushing’s) is characterized by numerous symptoms and a non-specific presentation, leading to a delay to diagnosis for patients with this disease. To date, research examining the lived experiences of patients with Cushing’s in healthcare is absent in the literature. This preliminary inquiry into the healthcare experiences of women with Cushing’s aimed to examine the utility of this line of inquiry to support the patient centered care of individuals with Cushing’s.

https://cushings.invisionzone.com/topic/57759-%E2%80%9Cthe-healthcare-system-did-fail-me-repeatedly%E2%80%9D-a-qualitative-study-on-experiences-of-healthcare-among-canadian-women-with-cushing%E2%80%99s-syndrome/

While American actress Amy Schumer is spreading the word about Cushing’s in general, I think that in some ways she is hurting things for everyone else.  CBS News reports that “she says she now feels ‘reborn’ after her diagnosis, and while some forms of Cushing can be fatal, she has a type that ‘will just work itself out.’”

How many others will try to get diagnosed and only be told not to worry, that it “will just work itself out”?

Read more at https://cushings.invisionzone.com/topic/56733-day-1-cushings-awareness-challenge-2022/?do=findComment&comment=478703

Cushing’s disease (CD) is a clinical syndrome caused by excessive secretion of adrenocorticotropic hormone (ACTH) from a pituitary corticotroph adenoma, resulting in adrenal cortical hyperplasia and overproduction of cortisol. The T-box transcription factor (TPIT) is crucial for regulating ACTH secretion in pituitary corticotroph adenomas. This study aims to explore the ubiquitin-mediated degradation of TPIT and identify potential pharmaceutical agents for treating CD.

https://cushings.invisionzone.com/topic/57874-the-stub1-tpit-axis-regulates-the-secretion-of-adrenocorticotrophic-hormone-in-cushing-disease/

Key takeaways:

• Cushing’s syndrome symptoms moderately impact quality of life for adults with the condition.
• Weight gain, muscle fatigue and menstrual changes decline in severity from diagnosis to follow-up.

Read more at https://cushings.invisionzone.com/topic/57630-adults-with-cushing%E2%80%99s-syndrome-report-high-burden-of-illness-despite-ongoing-treatment/

We report a case of a recently diagnosed adrenocorticotropic hormone (ACTH)-dependent Cushing's syndrome in a 30-years-old female who presented initially with a three-month history of progressive weight gain, generalized weakness, acne, menstrual irregularity, and severe hypokalemia, and then developed a gastric ulcer perforation only one month after her ACTH-dependent Cushing's syndrome diagnosis and was managed through emergent surgery.

Read more at https://cushings.invisionzone.com/topic/57659-adrenocorticotropic-hormone-dependent-cushings-syndrome-complicated-with-gastric-ulcer-perforation-in-a-30-year-old-saudi-female/

Cushing’s syndrome (CS) is associated with severe cardiovascular (CV) morbidity and mortality. Cardiac magnetic resonance (CMR) is the non-invasive gold standard for assessing cardiac structure and function; however, few CMR studies explore cardiac remodeling in patients exposed to chronic glucocorticoid (GC) excess. We aimed to describe the CMR features directly attributable to previous GC exposure in patients with cured or treated endogenous CS.

Read more at https://cushings.invisionzone.com/topic/57734-cardiac-magnetic-resonance-reveals-biventricular-impairment-in-cushing%E2%80%99s-syndrome/

Endogenous Cushing's syndrome (CS) has been linked with an increased risk of cancer. We aimed to evaluate the association between cancer risk and disease remission post-surgery in adrenal CS and Cushing's disease (CD).

https://cushings.invisionzone.com/topic/57786-impact-of-remission-status-in-endogenous-cushings-syndrome-on-cancer-incidence/

Graphic Era Hospital has achieved a remarkable mileston by successfully treating two complex cases of the rare hormonal disorder Cushing’s Disease in Dehradun. The hospital’s experts used advanced technology and surgical skills to give the patients a new lease on life, marking this significant achievement.

https://cushings.invisionzone.com/topic/57868-graphic-era-hospital%E2%80%99s-milestone-treatment-of-two-complex-cases/

We report the case of a 29-year-old male who presented with new-onset diabetes mellitus, resistant hypertension and significant weight gain. Physical examination revealed features consistent with Cushing’s syndrome. 

https://cushings.invisionzone.com/topic/57889-a-silent-invader-asymptomatic-rhodococcus-infection-unmasked-in-a-patient-with-ectopic-acth-dependent-cushing%E2%80%99s-syndrome/

Surgery beyond the age of 75, mainly relying on an endoscopic endonasal transsellar approach, is effective and safe, provided that patients are managed in tertiary centers.

Read more at https://cushings.invisionzone.com/topic/57640-pituitary-surgery-outcome-in-patients-75%C2%A0years-and-older/

In this study, we will investigate the possible side effects of psoriasis patients using long-term topical corticosteroids (TCS) such as adrenal insufficiency, Cushing’s Syndrome (CS) and osteoporosis and determine how these side effects develop.

Read more at https://cushings.invisionzone.com/topic/57678-evaluation-of-psoriasis-patients-with-long-term-topical-corticosteroids-for-their-risk-of-developing-adrenal-insufficiency-cushing%E2%80%99s-syndrome-and-osteoporosis/

The Phase III GRADIENT trial for relacorilant has missed its primary endpoint of improving SBP for Cushing's syndrome patients.

https://cushings.invisionzone.com/topic/57763-corcept%E2%80%99s-relacorilant-gradient-trial-misses-primary-endpoint/

Posterior pituitary tumors (PPTs) are extremely rare, with fewer than 400 cases reported to date. In 2022, the WHO classified four types of tumors originating from the posterior pituitary

Read more at https://cushings.invisionzone.com/topic/57780-oncocytic-pituicytoma-in-a-patient-with-cushings-disease/

Diagnosing Cushing's disease involves a series of tests to confirm excessive cortisol production and determine its source.

https://cushings.invisionzone.com/topic/57787-how-is-cushings-disease-diagnosed/

Has your doctor ever tried to dissuade you from using an alternative treatment?

Read more at https://cushings.invisionzone.com/topic/57567-what-do-you-think-alternative-treatments/

In patients diagnosed with the disease yet who had inconclusive MRI results, PET/MRI was positive in 100% of cases, noted lead author Ilanah Pruis, a doctoral student at Erasmus University Medical Center in Rotterdam, Netherlands.

“This multimodal imaging technique provides a welcome improvement for diagnosis, planning of surgery, and clinical outcome in patients with Cushing disease,” the authors wrote.

Read more at https://cushings.invisionzone.com/topic/57709-petmri-may-improve-diagnosis-of-cushing-disease/

Endogenous Cushing’s Syndrome (CS) is associated with an increased cardiovascular (CV) and metabolic risk profile, yet the specific impact of hypercortisolism on myocardial function remains inadequately understood.

https://cushings.invisionzone.com/topic/57805-myocardial-work-impairment-in-patients-with-cushing%E2%80%99s-syndrome/

Researchers from endocrinology and nuclear medicine departments have introduced a new PET scan molecule that enhances the detection of adenoma/small tumour causing Cushing’s syndrome. This development promises to improve surgical interventions and patient outcomes.

https://cushings.invisionzone.com/topic/57806-ivory-tower-new-pet-scan-molecule-offers-breakthrough-in-detecting-cushing%E2%80%99s-syndrome/

We present a 9-year-old boy who presented at age 4 with cyclical Cushing syndrome and was eventually diagnosed with a novel, previously unreported, unpublished variant in PRKAR1A associated with Carney complex. He was treated with unilateral left adrenalectomy. At 1-year follow-up, he continues to be in remission of his symptoms of Cushing syndrome.

https://cushings.invisionzone.com/topic/57870-unilateral-adrenalectomy-for-pediatric-cyclical-cushing-syndrome-with-novel-prkar1a-variant-associated-carney-complex/

Patients with Cushing’s disease (CD) experienced transient central adrenal insufficiency (CAI) after successful surgery. However, the reported recovery time of hypothalamic-pituitary-adrenal (HPA) axis varied and the risk factors which could affect recovery time of HPA axis had not been extensively studied. This study aimed to analyze the duration of CAI and explore the risk factors affecting HPA axis recovery in post-operative CD patients with biochemical remission.

Read more at https://cushings.invisionzone.com/topic/57581-preop-tt3-predicts-hpa-axis-recovery-after-cushing-surgery/

Cushing's syndrome is a rare cause of myocardial infarction and heart failure. Herein, we report a female patient who presented acute myocardial infarction and heart failure with reduced ejection fraction. The patient was found to have hypercortisolism secondary to adrenocortical adenoma and responded well to therapy. This case underlines the effects of hypercortisolism on the cardiovascular system. The clinical presentation of this patient is unique because non-atherosclerotic myocardial infarction is rarely reported in Cushing's syndrome patients.

Read more at https://cushings.invisionzone.com/topic/57660-cushings-syndrome-presenting-as-non-atherosclerotic-myocardial-infarction-and-heart-failure/

Dr. Friedman is an expert in pituitary, thyroid and adrenal issues as well as several other endocrine conditions, while most endocrinologists specialize in diabetes or just thyroid disease.  He has seen and diagnosed more patients with Cushing’s disease, growth hormone deficiency or adrenal insufficiency in a month than most Endocrinologists see in a lifetime.

https://cushings.invisionzone.com/topic/57822-reasons-you-or-your-friend-or-family-member-should-see-dr-friedman/

The most common cause of Cushing syndrome (CS) is exposure to exogenous glucocorticoids. There is an increasing incidence of adulterated over-the-counter (OTC) supplements containing steroids.

Read more at https://cushings.invisionzone.com/topic/57624-exogenous-cushing-syndrome-and-hip-fracture-due-to-over-the-counter-supplement-artri-king/

A 45-year-old female developed clinical and biochemical recurrent Cushings’ Disease 2.5 years after transsphenoidal hypophysectomy for 2cm pituitary macroadenoma.

Read more at https://cushingsbios.com/2024/07/02/anonymous-woman-recurrent-cushings/

The higher IGF-1 index was independently associated with lower prevalence of low bone mass in young CD patients, and IGF-1 might play an important role in the pathogenesis of CD-caused low bone mass.

Read more at https://cushings.invisionzone.com/topic/57619-association-of-igf-1-level-with-low-bone-mass-in-young-patients-with-cushing%E2%80%99s-disease/

Even though this was from two years ago, I don't think that there have been any significant changes in the many symptoms of Cushing's. 

Today's News Item proclaimed loftily  

Quote

In patients diagnosed with the disease yet who had inconclusive MRI results, PET/MRI was positive in 100% of cases, noted lead author Ilanah Pruis, a doctoral student at Erasmus University Medical Center in Rotterdam, Netherlands.

“This multimodal imaging technique provides a welcome improvement for diagnosis, planning of surgery, and clinical outcome in patients with Cushing disease,” the authors wrote.

But will enough doctors actually allow patients to get that far or will they still blow them off?

From https://cushings.invisionzone.com/topic/56737-day-2-cushing%E2%80%99s-awareness-challenge-2022/?do=findComment&comment=478717

Endocrinologic evaluation revealed grossly elevated 24-hour urinary free cortisol and elevated serum cortisol levels consistent with severe Cushing’s syndrome, and she was started on high-dose ketoconazole.

Read more at https://cushings.invisionzone.com/topic/57592-an-aggressive-case-of-adrenocortical-carcinoma-complicated-by-paraneoplastic-cushing%E2%80%99s-syndrome/

We present a patient with Cushing syndrome secondary to accidental intake of corticosteroid tablets—a 66-year-old woman with a history of well-controlled hypertension, who over the course of a few weeks developed full-blown Cushing syndrome with uncontrolled blood pressure, typical central fat accumulation, and easy bruising.

Read more at https://cushings.invisionzone.com/topic/57688-accidental-cushing-syndrome/

Did't we all do this?

A young woman saved her own life after successfully self-diagnosing cancer/Cushing's that doctors had missed because she researched her own worrying symptoms on TikTok.

https://cushings.invisionzone.com/topic/57819-tiktok-saved-my-life-student-discovers-life-threatening-tumour-after-self-diagnosing-rare-condition/

Graphic Era Hospital has achieved a remarkable mileston by successfully treating two complex cases of the rare hormonal disorder Cushing’s Disease in Dehradun. The hospital’s experts used advanced technology and surgical skills to give the patients a new lease on life, marking this significant achievement.

https://cushings.invisionzone.com/topic/57868-graphic-era-hospital%E2%80%99s-milestone-treatment-of-two-complex-cases/

Posterior pituitary tumors (PPTs) are extremely rare, with fewer than 400 cases reported to date. In 2022, the WHO classified four types of tumors originating from the posterior pituitary

Read more at https://cushings.invisionzone.com/topic/57780-oncocytic-pituicytoma-in-a-patient-with-cushings-disease/

Cushing’s Disease is common in dogs but rare and hard to diagnose in people. That’s why University of Georgia researchers are leveraging canine treatments to find new solutions to battle the condition in humans. This collaboration between veterinary medicine and human health care is just one example of how UGA uses a Precision One Health approach to find and tailor new medical treatments for people and animals.

https://cushings.invisionzone.com/topic/57820-connecting-canine-and-human-health-to-fight-cushing%E2%80%99s-disease/

We present a 9-year-old boy who presented at age 4 with cyclical Cushing syndrome and was eventually diagnosed with a novel, previously unreported, unpublished variant in PRKAR1A associated with Carney complex. He was treated with unilateral left adrenalectomy. At 1-year follow-up, he continues to be in remission of his symptoms of Cushing syndrome.

https://cushings.invisionzone.com/topic/57870-unilateral-adrenalectomy-for-pediatric-cyclical-cushing-syndrome-with-novel-prkar1a-variant-associated-carney-complex/

Wow - a lot has happened since I first shared this post.  If you look at the timestamp, I'm writing this at 4:20 am and I've been awake for an hour, even though I'm exhausted.

I have been back on Growth Hormone although it doesn't seem to do me any good.

Read more at https://cushings.invisionzone.com/topic/56745-day-3-cushing%E2%80%99s-awareness-challenge-2022/?do=findComment&comment=478719

The patient is a 46-year-old male who presented to our hospital with recurrent symptoms of pheochromocytoma. He reported that he experienced unexplained symptoms such as panic attacks, headache, sweating, nausea, vomiting, and a feeling of imminent death, which could be alleviated by rest. 

Read more at https://cushings.invisionzone.com/topic/57698-ectopic-adrenocorticotropic-hormone-secreting-pheochromocytoma-with-severe-metabolic-disturbances-a-case-report/

Adrenal insufficiency is a condition where the adrenal glands don't produce enough of certain hormones, primarily cortisol and sometimes aldosterone. This disorder can be categorized into primary (Addison's disease) and secondary forms.

https://cushings.invisionzone.com/topic/57788-adrenal-insufficiency/

Evaluate whether age-related differences exist in clinical characteristics, diagnostic approach and management strategies in patients with Cushing’s syndrome included in the European Registry on Cushing’s Syndrome (ERCUSYN).

Read more at https://cushings.invisionzone.com/topic/57599-cushing%E2%80%99s-syndrome-in-the-elderly-data-from-the-european-registry-on-cushing%E2%80%99s-syndrome/

The most common cause of Cushing syndrome (CS) is exposure to exogenous glucocorticoids. There is an increasing incidence of adulterated over-the-counter (OTC) supplements containing steroids.

Read more at https://cushings.invisionzone.com/topic/57624-exogenous-cushing-syndrome-and-hip-fracture-due-to-over-the-counter-supplement-artri-king/

I have recently been diagnosed with cushings syndrome and awaiting removal of gland and tumour.

https://cushingsbios.com/2025/11/07/janet-janetelizabeth-adrenal-bio/

The higher IGF-1 index was independently associated with lower prevalence of low bone mass in young CD patients, and IGF-1 might play an important role in the pathogenesis of CD-caused low bone mass.

Read more at https://cushings.invisionzone.com/topic/57619-association-of-igf-1-level-with-low-bone-mass-in-young-patients-with-cushing%E2%80%99s-disease/

Dr. Karen Thames shared these on her Facebook Page, Empowering People with Invisible Chronic Illness – The EPIC Foundation

She has graciously given me permission to share them here and in the CushieWiki and on the Cushing’s Help message boards.

Read more at https://cushieblogger.com/2022/04/03/cushings-myths-and-facts-4/

Like most everything else in my life, having had Cushing's (pituitary) made this surgery more difficult.  My surgeon had to plan with my endocrinologist how much cortisol I'd need during the operation, then I had to stay overnight to get me successfully weaned off the cortisone again.

Read more at https://cushings.invisionzone.com/topic/57682-what-was-the-most-memorable-thing-that-happened-to-you-last-year/

Cortisol is a hormone which produced by the adrenal gland (cortex) to control blood sugar. The production of cortisol is triggered by the pituitary hormone ACTH. Cortisol is a glucocorticoid which stimulates an increase in blood glucose. Cortisol will also stimulate the release of amino acids from muscle tissue and fatty acids from adipose tissue. The amino acids are then converted in the liver to glucose (for use by the brain). The fatty acids can be used by skeletal muscles for energy (rather than glucose) thereby freeing up glucose for selective utilization by the brain. Cortisol levels are often measured to evaluate the function of the pituitary or adrenal glands. Some of the cortisol is metabolized by the liver to produce 17 hydroxycorticosteroids, which is then excreted in the urine.

Read more at https://cushings.invisionzone.com/topic/56255-what-is-cortisol/

Diabetic ketoacidosis is an exceptionally rare initial manifestation of ectopic adrenocorticotropic hormone (ACTH) syndrome. A 42-year-old woman with multiple cardiovascular risk factors was admitted to the emergency room with diabetic ketoacidosis. 

https://cushings.invisionzone.com/topic/57925-diabetic-ketoacidosis-as-the-first-manifestation-of-ectopic-cushing%E2%80%99s-syndrome/

Bilateral adrenalectomy (BA) still plays an important role in the management of Cushing's disease (CD). Nelson’s syndrome (NS) is a severe complication of BA, but conflicting data on its prevalence and predicting factors have been reported. The aim of this study was to determine the prevalence of NS, and identify factors associated with its development.

Read more at https://cushings.invisionzone.com/topic/55708-prevalence-of-nelson%E2%80%99s-syndrome-after-bilateral-adrenalectomy-in-patients-with-cushing%E2%80%99s-disease/

Cases of hepatotoxicity with fatal outcome or requiring liver transplantation have been reported with oral ketoconazole. Some patients had no obvious risk factors for liver disease. Recorlev is associated with serious hepatotoxicity. Evaluate liver enzymes prior to and during treatment.

Read more at https://cushings.invisionzone.com/topic/57735-xeris-presents-new-post-hoc-analysis-on-effects-of-levoketoconazole-recorlev%C2%AE-in-cushing%E2%80%99s-syndrome-patients-at-endo-2024/

Graphic Era Hospital has achieved a remarkable mileston by successfully treating two complex cases of the rare hormonal disorder Cushing’s Disease in Dehradun. The hospital’s experts used advanced technology and surgical skills to give the patients a new lease on life, marking this significant achievement.

https://cushings.invisionzone.com/topic/57868-graphic-era-hospital%E2%80%99s-milestone-treatment-of-two-complex-cases/

This case highlights the necessity of providers to be aware of potential complications of endocrinological disorders. The risk of thromboembolism is more commonly present in patients with Cushing syndrome, who have risk factors such as obesity, surgery and invasive diagnostic procedures.

https://cushings.invisionzone.com/topic/57876-hypercoagulability-in-cushing-syndrome/

Through the newly available dial-up internet, I joined forces with a small group of wonderful Cushing’s advocates. Cathy Gifford and Mary O’Connor, were my first Cushing’s friends, and are still dear friends twenty one years later. Together we got things moving. Mary, has built the largest Cushing’s support boards, and her admirable dedication continues to help and support patients from all over the world, Cushing’s Help and Support (cushings-help.com).

Read more at https://cushieblogger.com/2022/04/03/kind-words-for-cushings-awareness-month/

Posterior pituitary tumors (PPTs) are extremely rare, with fewer than 400 cases reported to date. In 2022, the WHO classified four types of tumors originating from the posterior pituitary

Read more at https://cushings.invisionzone.com/topic/57780-oncocytic-pituicytoma-in-a-patient-with-cushings-disease/

The pituitary gland produces hormones. A tumor in this gland can cause it to produce too much of the hormone cortisol. Too much cortisol in the body causes Cushing disease. This disease causes many problems. Some of these problems might persist after the disease is cured.

Read more at https://cushings.invisionzone.com/topic/56742-long-term-follow-up-of-survivors-of-pediatric-cushing-disease/

We’re looking for caregivers to loved ones diagnosed with Cushing's Disease or patients diagnosed with Cushing's Disease to participate in a research study. 

 Who: Patients and caregivers of loved ones

 What: 30-minute Online Survey

 Compensation: $60.00

Sign up here: https://rarepatientvoice.com/CushingsHelp/

Sharmyn McGraw searched for answers for seven years for whatever it was that was killing her; finally she diagnosed herself via the Internet with Cushing’s disease, caused by a pituitary brain tumor. 

See the video at https://cushieblogger.com/2019/04/03/video-cushings-disease-pituitary-gland/