Lenise passed away Wednesday, Oct. 2, 2002 at 23 years old, just after her surgery.

Read more at https://cushingsbios.com/2021/10/02/in-memory-of-lenise-petersen-october-2-2002-3/

The hypothalamic-pituitary-adrenal axis stimulation during pregnancy complicates the investigation of Cushing's syndrome. Our objective is to present a pregnant patient with Cushing syndrome caused by pituitary tumor in which the desmopressin stimulation test helped in the diagnosis and led to appropriate management.

Read more at https://cushings.invisionzone.com/topic/56326-desmopressin-stimulation-test-in-a-pregnant-patient-with-cushing%E2%80%99s-disease/

Patients with neuroendocrine tumors before ectopic Cushing syndrome development were more likely metastatic and had worse survival

Read more at https://cushings.invisionzone.com/topic/56894-management-of-adrenocorticotropic-hormone-secreting-neuroendocrine-tumors-and-the-role-of-bilateral-adrenalectomy-in-ectopic-cushing-syndrome/

 Cushing syndrome can present with wide range of neuropsychiatric manifestations including major depression. Although presentation with suicidal depression is unusual. Early diagnosis and prompt management of hypercortisolsim may aid in preventing or lessening of psychiatric symptoms.

Read more at https://cushings.invisionzone.com/topic/56245-a-case-of-cushing%E2%80%99s-disease-presenting-with-isolated-suicidal-attempt/

...Being constantly diagnosed as “healthy” caused me to be told, when I was finally diagnosed correctly, that I had maybe five years to live. Misdiagnosis can be a killer.… It is now my personal mission and obligation to help those suffering from any chronic illness that steals your joy, and bring awareness to Endocrine Disorders. From my journey through Cushing’s to Addison’s to recovery—from triathlete to barely being able to dress myself and finally to recovering into a stronger person I never knew I was.

Read more at https://amzn.to/2pWMhOh

In Cushing’s syndrome (CS), chronic glucocorticoid excess (GC) and disrupted circadian rhythm lead to insulin resistance (IR), diabetes mellitus, dyslipidaemia and cardiovascular comorbidities. As undifferentiated, self-renewing progenitors of adipocytes, mesenchymal stem cells (MSCs) may display the detrimental effects of excess GC, thus revealing a promising model to study the molecular mechanisms underlying the metabolic complications of CS.

Read more at https://cushings.invisionzone.com/topic/56741-a-promising-in-vitro-model-to-study-cushing%E2%80%99s-syndrome/

Thursday, October 3, 2002

Alice died of lung cancer and Cushing’s.

Read more at https://cushingsbios.com/2021/10/03/in-memory-alice-baker-october-3-2002/

In 2015, Charly came home for a visit, and went to see her GP about her lack of periods and a blind spot in her peripheral vision. An MRI scan showed a mass on her brain. ‘They said it had eroded the bone in my nose and was pressing on the optic nerve, and it was lucky we had caught it,’ she says. ‘The next step would have been discovering it because I’d gone blind.’

Read more at https://cushings.invisionzone.com/topic/56330-actress-charly-clive-pituitary-adenoma/

Patients with neuroendocrine tumors before ectopic Cushing syndrome development were more likely metastatic and had worse survival

Read more at https://cushings.invisionzone.com/topic/56894-management-of-adrenocorticotropic-hormone-secreting-neuroendocrine-tumors-and-the-role-of-bilateral-adrenalectomy-in-ectopic-cushing-syndrome/

Dr. Karen Thames shared these on her Facebook Page, Empowering People with Invisible Chronic Illness – The EPIC Foundation

She has graciously given me permission to share them here and in the CushieWiki and on the Cushing’s Help message boards.

Read more at https://cushieblogger.com/2022/04/03/cushings-myths-and-facts-4/

 Cushing syndrome can present with wide range of neuropsychiatric manifestations including major depression. Although presentation with suicidal depression is unusual. Early diagnosis and prompt management of hypercortisolsim may aid in preventing or lessening of psychiatric symptoms.

Read more at https://cushings.invisionzone.com/topic/56245-a-case-of-cushing%E2%80%99s-disease-presenting-with-isolated-suicidal-attempt/

In Cushing’s syndrome clinical care and clinical trials, the standard way for someone's cortisol level to be measured is a 24-hour urine collection,” states Katz. “That involves looking at the amount of cortisol in the urine over a 24-hour period. That collection is inconvenient and burdensome, and the patient must then carry it somewhere to be analyzed.”

Sparrow hopes to shift that collection to a spot urine sample, like what patients would experience during a physical...

Read more at https://cushings.invisionzone.com/topic/56246-sparrow-pharmaceuticals-hopes-to-change-the-future-of-endocrinology/

Through the newly available dial-up internet, I joined forces with a small group of wonderful Cushing’s advocates. Cathy Gifford and Mary O’Connor, were my first Cushing’s friends, and are still dear friends twenty one years later. Together we got things moving. Mary, has built the largest Cushing’s support boards, and her admirable dedication continues to help and support patients from all over the world, Cushing’s Help and Support (cushings-help.com).

Read more at https://cushieblogger.com/2022/04/03/kind-words-for-cushings-awareness-month/

This breaks my heart. Liz was so young. She was finally so hopeful after way too long. We have to do something to change this. People especially doctors have to know what we go through. Mary is one person and look at all she has done to raise awareness. We are so many. There has to be something we all can do. 

Read more at https://cushingsbios.com/2021/03/01/in-memory-liz-raftery-march-2012/

Sharmyn McGraw searched for answers for seven years for whatever it was that was killing her; finally she diagnosed herself via the Internet with Cushing’s disease, caused by a pituitary brain tumor. 

See the video at https://cushieblogger.com/2019/04/03/video-cushings-disease-pituitary-gland/

One of my least favorite things about my life with chronic illness is having imaging appointments.  Whether it's my yearly brain MRI, or a chest X-ray, the whole process is uncomfortable, and sometimes even painful...

Read more at https://cushieblogger.com/2019/04/03/from-a-past-blogging-challenge-cushings-awareness-challenge-danielle-day-3/

The Add Your Bio form has been updated so that it no longer requires Flash. Your information will help others.

I would like to add that if anyone would like to do something for the Cushing's Awareness Challenge but you don't have (or want to have) a blog, why not consider adding your bio to the website this month?

More info at https://cushingsbios.com/2018/08/28/we-have-a-new-bio-form/

This was a challenging condition and requires a multidisciplinary approach in diagnosis and management, which can be very difficult in resource-limited areas. In addition, a delay in diagnosis and management often results in rapid deterioration of clinical status.

Read more at https://cushings.invisionzone.com/topic/56339-final-diagnosis-acth-dependent-cushing%E2%80%99s-syndrome-%E2%80%A2-ectopic-acth-syndrome/

Osilodrostat is associated with rapid normalization of mean urinary free cortisol (mUFC) excretion in patients with Cushing disease and has a favorable safety profile, according to the results of a study published in the Journal of Clinical Endocrinology & Metabolism.

Read more at https://cushings.invisionzone.com/topic/56896-osilodrostat-effective-for-patients-with-cushing-disease/

Patients with neuroendocrine tumors before ectopic Cushing syndrome development were more likely metastatic and had worse survival

Read more at https://cushings.invisionzone.com/topic/56894-management-of-adrenocorticotropic-hormone-secreting-neuroendocrine-tumors-and-the-role-of-bilateral-adrenalectomy-in-ectopic-cushing-syndrome/

 Cushing syndrome can present with wide range of neuropsychiatric manifestations including major depression. Although presentation with suicidal depression is unusual. Early diagnosis and prompt management of hypercortisolsim may aid in preventing or lessening of psychiatric symptoms.

Read more at https://cushings.invisionzone.com/topic/56245-a-case-of-cushing%E2%80%99s-disease-presenting-with-isolated-suicidal-attempt/

“The pituitary is commonly referred to as the ‘master’ gland because it does so many important jobs in the body,” says Karen Frankwich, MD, a board-certified endocrinologist at Mission Hospital. “Not only does the pituitary make its own hormones, but it also triggers hormone production in other glands. The pituitary is aided in its job by the hypothalamus. This part of the brain is situated above the pituitary, and sends messages to the gland on when to release or stimulate production of necessary hormones.”

Read more at https://cushings.invisionzone.com/topic/56334-the-pituitary-gland-small-but-mighty/

Stress-related brain disorders can be associated with glucocorticoid disturbance and hippocampal alteration. However, it remains largely unknown how cortisol affects the structure and function of hippocampus. Cushing's disease (CD) provides a unique “hyperexpression model” to explore the effects of excessive cortisol on hippocampus as well as the relation between these effects and neuropsychological deficits.

Read more at https://cushings.invisionzone.com/topic/56924-altered-hippocampal-volume-and-functional-connectivity-in-patients-with-cushings-disease/

My step daughter is really dragging on getting timely care for what appears to be Cushing Syndrome. The symptoms have been going on for years. She has an adrenal tumor that needs to be moved and an abdominal hernia that needs repair. My husband and I are very worried and frustrated about the deteriorating effects on her health. She is extremely reluctance to listen to our concerns or our advice. I wish too that we could get some advice about how to help her

More at https://cushings.invisionzone.com/topic/55721-adult-child-with-cushings/#comment-476626

I have often said, I wish I had cancer instead.  Most people would not understand this sentiment, why in the world would you wish for such a horrible disease?...

Read more at https://cushieblogger.com/2019/04/04/from-a-past-blogging-challenge-cushings-awareness-challenge-danielle-day-4/

Interview with Judy, the mother of two Cushing’s patients, and her daughter, Jess, a high school student with Cushing’s. Robin (staticnrg) hosted.

Read more at https://cushieblogger.com/2022/04/11/archived-interview-with-judy-mom-to-two-cushings-patients-and-her-daughter-jess-3/

Cushing’s disease is a progressive pituitary disorder in which there is an excess of cortisol in the body. While the disease can be treated surgically, this option is not possible for all patients. This is one of the approved medications that assist in controlling cortisol levels in people with Cushing’s disease.

Isturisa was approved in 2020 to treat adults with Cushing’s disease for whom pituitary surgery is ineffective or not an option.

Read more at https://cushings.invisionzone.com/topic/56571-meds-isturisa/

Ectopic pituitary adenoma (EPA) is a pituitary adenoma unrelated to the intrasellar component and is an extremely rare disease.

Read more at https://cushings.invisionzone.com/topic/57535-ectopic-adrenocorticotropic-hormone-secreting-pituitary-adenoma-in-the-clivus-region-a-case-report/

TSH stands for “thyroid stimulating hormone” and the test measures how much of this hormone is in your blood. TSH is produced by the pituitary gland in your brain. This gland tells your thyroid to make and release the thyroid hormones into your blood.

Read more at https://cushings.invisionzone.com/topic/56343-basics-testing-what-is-a-tsh-test/

Patients with neuroendocrine tumors before ectopic Cushing syndrome development were more likely metastatic and had worse survival

Read more at https://cushings.invisionzone.com/topic/56894-management-of-adrenocorticotropic-hormone-secreting-neuroendocrine-tumors-and-the-role-of-bilateral-adrenalectomy-in-ectopic-cushing-syndrome/

 Cushing syndrome can present with wide range of neuropsychiatric manifestations including major depression. Although presentation with suicidal depression is unusual. Early diagnosis and prompt management of hypercortisolsim may aid in preventing or lessening of psychiatric symptoms.

Read more at https://cushings.invisionzone.com/topic/56245-a-case-of-cushing%E2%80%99s-disease-presenting-with-isolated-suicidal-attempt/

This report describes the case of a patient whose pituitary microadenoma resolved after he contracted coronavirus disease 2019. To our knowledge, this is one of the first reported cases of pituitary tumor resolution due to viral illness. 

Read more at https://cushings.invisionzone.com/topic/56247-resolution-of-pituitary-microadenoma-after-coronavirus-disease-2019-a-case-report/

We discuss the case of a 60-year-old woman with recurrent venous thromboembolism, refractory hypokalemia, and lumbar vertebrae compression fractures with a rapidly progressive disease course. Ectopic hypercortisolism was suspected given the patient’s age and rapid onset of disease. 

Read more at https://cushings.invisionzone.com/topic/56250-acute-severe-cushings-disease-presenting-as-a-hypercoagulable-state/

Help Rare Patient Voice spread the word to other patients and caregivers about RPV by submitting a short video on your experience with us. Check out the growing group of patients and caregivers who have recorded stories: https://rarepatientvoice.com#sharevoice.

Read more at https://cushings.invisionzone.com/topic/56677-record-a-video-receive-a-rarity-t-shirt/

Social media dominates most people's lives these days. You see what everyone you know is up to, but the problem is, most people only post about the highlights of their lives.

You don't get to see the low points, the every day struggles. You don't see what keeps them up at night with worry...

Read more at https://cushieblogger.com/2019/04/05/from-a-past-blogging-challenge-cushings-awareness-challenge-danielle-day-5/

A 35-year-old woman is seen in the outpatient clinic for evaluation of an incidental pituitary macroadenoma. Her medical history is significant for hypertension, diabetes, hyperlipidemia, polycystic ovary syndrome, and obesity. She initially presented to the emergency department (ED) a week ago after an episode of right visual field changes that she described as waviness in her right eye and right hemibody sensory changes without motor deficits. While in the ED, she underwent a full workup for possible stroke, which was negative. Magnetic resonance imaging (MRI) of her brain without contrast revealed a 12-mm pituitary lesion; a repeat MRI with contrast was then ordered (Figure). No serum hormonal panel was available for review from ED records. 

Read more at https://cushings.invisionzone.com/topic/56643-workup-for-incidental-pituitary-adenoma/

Interview with Alicia, a Cushing’s Message Board member who is still testing. Alicia writes “Around the end of my Junior year, probably one of the worst things that could have happened during my 8 years of illness happened, I had severe psychiatric symptoms at school, including psychosis, and was put on a “students in crisis” plan and sent home for a little while. Being diagnosed as a “psych patient” would delay my diagnosis for years, most doctors just considered me “crazy.”

Read more at https://cushieblogger.com/2019/04/05/archived-interview-with-alicia-a-patient-who-is-still-testing/

Myth: “Cushing’s is RARE”, “No one has Cushing’s!”, “It is literally impossible for you to have Cushing’s Disease!”

Read more at https://cushieblogger.com/2021/04/04/cushings-myths-and-facts-cushings-is-rare-no-one-has-cushings-3/

As many as 1 in 10 people have a non-cancerous tumor on one or both of their adrenal glands that could cause the gland to produce excess amounts of the stress hormone cortisol.

Read more at https://cushings.invisionzone.com/topic/56446-benign-adrenal-gland-tumors-might-cause-harm-to-millions/

Patients with neuroendocrine tumors before ectopic Cushing syndrome development were more likely metastatic and had worse survival

Read more at https://cushings.invisionzone.com/topic/56894-management-of-adrenocorticotropic-hormone-secreting-neuroendocrine-tumors-and-the-role-of-bilateral-adrenalectomy-in-ectopic-cushing-syndrome/

 Cushing syndrome can present with wide range of neuropsychiatric manifestations including major depression. Although presentation with suicidal depression is unusual. Early diagnosis and prompt management of hypercortisolsim may aid in preventing or lessening of psychiatric symptoms.

Read more at https://cushings.invisionzone.com/topic/56245-a-case-of-cushing%E2%80%99s-disease-presenting-with-isolated-suicidal-attempt/

Clinical Relevance: Cushing’s Disease (CD) in pregnancy is a rare, but serious, disease that has potential adverse effects on maternal and fetal health. Surgery is considered first line therapy, and there is little consensus on medical treatment of CD in pregnancy. This CASE demonstrates the successful use and titration of metyrapone throughout pregnancy.

Read more at https://cushings.invisionzone.com/topic/56254-cushing-disease-treated-successfully-with-metyrapone-during-pregnancy/

Despite improved outcomes in recent years, increased mortality from CS persists. The causes of death highlight the need to prevent and manage co-morbidities in addition to treating hypercortisolism.

Read more at https://cushings.invisionzone.com/topic/56897-the-effect-of-endogenous-cushings-syndrome-on-all-cause-and-cause-specific-mortality/

Sharmyn McGraw knows as much about pituitary disease as some doctors. She learned about it after struggling for years with a medical mystery that began in 1993.

First, she began to feel anxious. Then, she began to gain weight, and she developed a rash. Much of her hair fell out. Her eyes began to yellow and her face puffed up.

Read more at https://cushings.invisionzone.com/topic/56898-tracking-a-mystery-disease-to-the-pituitary-gland-sharmyn-mcgraw/

The novel protocol and diagnostic method for adrenal tumors will condense a 2–4-week process of localization of hyper-secreting adrenal tumors and subsequent curative surgery down to just one day. The innovative approach combines highly specialized adrenal vein sampling with rapid adrenal hormone lab testing and then consultation with the world's highest volume adrenal surgeon. If appropriate, a patient may even complete their mini-surgery during that same visit.

Read more at https://cushings.invisionzone.com/topic/56260-innovative-one-visit-adrenal-tumor-diagnosis-and-treatment-program-begins-in-tampa/

Patients with neuroendocrine tumors before ectopic Cushing syndrome development were more likely metastatic and had worse survival

Read more at https://cushings.invisionzone.com/topic/56894-management-of-adrenocorticotropic-hormone-secreting-neuroendocrine-tumors-and-the-role-of-bilateral-adrenalectomy-in-ectopic-cushing-syndrome/

 Cushing syndrome can present with wide range of neuropsychiatric manifestations including major depression. Although presentation with suicidal depression is unusual. Early diagnosis and prompt management of hypercortisolsim may aid in preventing or lessening of psychiatric symptoms.

Read more at https://cushings.invisionzone.com/topic/56245-a-case-of-cushing%E2%80%99s-disease-presenting-with-isolated-suicidal-attempt/

I pray for your agony to let up and give you a break!! This is the most exhausting almost unexplainable damaging heartbreaking thing I’ve gone through in my life. Gentle hugs. Prayers too?

We describe the first report of recurrent Cushing's Disease that was quiescent during pregnancy and diagnosed in the immediate postpartum period. Understanding the risk and mechanisms of CD recurrence in pregnancy allows us to counsel these otherwise healthy, reproductive-age women in the context of additional family planning.

Read more at https://cushings.invisionzone.com/topic/57548-persistent-vs-recurrent-cushing%E2%80%99s-disease-diagnosed-four-weeks-postpartum/

[t]he degree of change in exposure of mifepristone when co-administered with strong CYP3A inhibitors is unknown” and “may present a safety risk.”  The concern was that without the required study the patients with Cushing’s syndrome that take strong inhibitors may be unable to use mifepristone.

Read more at https://cushings.invisionzone.com/topic/56453-korlym-failure-to-show-a-reasonable-expectation-of-success-dooms-obviousness-allegations/

Dear friends and family:

I am writing this letter to share with you some basic facts about Cushing’s Disease/Syndrome and the recovery process so that you will have sufficient information to form realistic expectations about me and my ability to engage in certain activities in light of this disease and its aftermath.

As you know, Cushing’s is a rarely diagnosed endocrine disorder characterized by hypercortisolism. 

Read more at https://cushings.invisionzone.com/topic/56191-family-information-kate/

Cushing’s syndrome (CS) is a rare condition of chronically elevated cortisol levels resulting in diverse comorbidities, many of which endure beyond successful treatment affecting the quality of life. Few data are available concerning patients’ experiences of diagnosis, care and persistent comorbidities.

Read more at https://cushings.invisionzone.com/topic/57550-unmet-needs-in-cushing%E2%80%99s-syndrome-the-patients/

Long-standing studies were conducted on vitamin D levels in patients with Cushing's Disease. Patients with CD, with and without osteopenia, were compared before and after oral calcium load showing that serum 1,25 (OH)2D3 plasma levels were higher in subjects with osteopenia than in those without it, likely due to a secondary increase in PTH levels as an effect of hypercortisolism [19]. Another study investigated the effect of hypercortisolism and eucortisolism, showing a reduction in serum 25(OH)D levels, but not in 1,25 (OH)2D3 in patients with hypercortisolism. 

Read more at https://cushings.invisionzone.com/topic/56652-vitamin-d-deficiency-in-cushing%E2%80%99s-disease-before-and-after-its-supplementation/

Carlin is from the Napa Valley CA. USA.

I’m 66 yo and have recovered from Cushings but now take hydrocortisone, thyroxine, ddavp and citalopram. It’s was a real fight to find a dr who believed me. (my GP said I was a morbidly obese hypochondriac).

Read more at https://cushingsbios.com/2022/02/12/carlin-recovered-from-pituitary-tumor/

The endocrine system is a complex network of glands and organs. It uses hormones to control and coordinate your body's metabolism, energy level, reproduction, growth and development, and response to injury, stress, and mood. The following are integral parts of the endocrine system..

Read more at https://cushings.invisionzone.com/topic/56271-the-endocrine-system/

Patients with neuroendocrine tumors before ectopic Cushing syndrome development were more likely metastatic and had worse survival

Read more at https://cushings.invisionzone.com/topic/56894-management-of-adrenocorticotropic-hormone-secreting-neuroendocrine-tumors-and-the-role-of-bilateral-adrenalectomy-in-ectopic-cushing-syndrome/

I'm on a medication which interferes with the dexamethasone suppression tests. I tried going off the medication, but wasn't able to do so. I've taken saliva and 24 urine tests. I have many of the symptoms.

Read more here: https://cushings.invisionzone.com/topic/57202-difficulty-diagnosing-cushing-syndrome/

 In this CME Webinar, #endocrinology experts in the management of #CushingsDisease will describe best practices for the diagnosis and treatment to improve long-term outcomes for patients.

Read more at https://cushings.invisionzone.com/topic/57242-webinar-best-practices-for-the-management-of-individuals-with-cushings-disease/

Chronic insomnia can be a sign of Cushing’s syndrome, and doctors need be aware of this possibility, according to a case report of a woman diagnosed with Cushing’s shortly after seeking help for her insomnia.

This case also emphasized the usefulness of the dexamethasone suppression test in identifying the specific cause of Cushing’s.

Read more at https://cushings.invisionzone.com/topic/55648-chronic-insomnia-can-be-sign-of-cushing%E2%80%99s/

This is a video is on the HPA Axis.

You may have to sign up/log in to view this video but Coursera is free – and you might find other courses of interest!

Read more at https://cushieblog.com/2015/02/06/hypothalamus-pituitary-adrenal-axis/

A chronic, progressive disease was discovered to be the reason why a man in his 20s experienced a sudden increase of gray hair and facial changes, local doctors said…

Doctors suspected he suffered from acromegaly, a chronic disease characterized by enlargement of head bones, soft parts of the feet and hands and sometimes other parts of the body due to excessive secretion of growth hormones by the pituitary gland.

Read more at https://cushings.invisionzone.com/topic/55649-chronic-disease-root-of-young-mans-abnormally-gray-hair-and-facial-changes/

 Cushing syndrome can present with wide range of neuropsychiatric manifestations including major depression. Although presentation with suicidal depression is unusual. Early diagnosis and prompt management of hypercortisolsim may aid in preventing or lessening of psychiatric symptoms.

Read more at https://cushings.invisionzone.com/topic/56245-a-case-of-cushing%E2%80%99s-disease-presenting-with-isolated-suicidal-attempt/

Many people on the message boards see Dr. Kirschner for adrenal issues.

See the short video at https://cushings.invisionzone.com/topic/56786-helpful-doctors-ohio/

The most common etiologies of Cushing's syndrome (CS) are adrenocorticotropic hormone (ACTH)-producing pituitary adenoma (pitCS) and primary adrenal gland disease (adrCS), both of which burden patients with metabolic disturbance. The aim of this study was to compare the metabolic features of pitCS and adrCS patients.

Read more at https://cushings.invisionzone.com/topic/56190-metabolic-profile-differences-in-acth-dependent-and-acth-independent-cushing-syndrome/

Acute adrenal crisis is a life-threatening state caused by insufficient levels of cortisol, which is a hormone produced and released by the adrenal gland.

Read more at https://cushings.invisionzone.com/topic/56238-call-911-adrenal-crisis-addisonsadrenal-insufficiency/

Fact: NO! Caloric intake or lack of exercise has NO impact on weight gain and/ or loss in persons with Cushing’s...

Read more at https://cushieblogger.com/2022/04/09/cushings-myths-and-facts-cushings-syndrome-disease-can-be-healed-or-cured-2/

Listen as Jayne Kerns and Robin Smith (staticnrg) hosted a Cushing’s Awareness Day Special Chat.

Read more at https://cushieblogger.com/2022/04/08/archived-cushings-awareness-day-voice-chat-2/

Corcept last year made over $353 million from sales of Korlym, the company's only drug, according to a filing with the U.S. Securities and Exchange Commission.

Corcept's patent relates to using a specific dose of Korlym's active ingredient mifepristone and another drug to treat Cushing's syndrome, which creates an excess of the hormone cortisol and causes high blood sugar, among other things.

Read more at https://cushings.invisionzone.com/topic/56355-no-synthetic-steroid-version-of-korlym-at-this-time/

Compared with placebo, levoketoconazole improved cortisol control and serum cholesterol levels for adults with endogenous Cushing’s syndrome

Read more at https://cushings.invisionzone.com/topic/56902-levoketoconazole-improves-cortisol-control-in-endogenous-cushing%E2%80%99s-syndrome/